Judge Leon Motte founded the school in Wilmington, North Carolina, in 1916, and initially specialized in stenographic instruction. Since that time, Miller-Motte has continued to develop new programs and open new locations.

In 1987, the college opened a campus in Clarksville, Tennessee. Due to expansion in this area, a new
facility was built in its current location at 1820 Business Park Drive. The Clarksville Campus applied for and was granted stand-alone accreditation through the Association of Independent Colleges and Schools in 1989. In 1998, Delta Education Systems, Inc. purchased Miller-Motte. There is now a branch in Wilmington, North Carolina and Charleston, SC.

Miller-Motte Technical College provides career training designed to prepare students with the essential skills and knowledge needed to become productive employees.